ATP5L2 Antibody - #DF3807

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Product: ATP5L2 Antibody
Catalog: DF3807
Description: Rabbit polyclonal antibody to ATP5L2
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 20 KD; 11kD(Calculated).
Uniprot: Q7Z4Y8
RRID: AB_2836164

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
ATP5L2 Antibody detects endogenous levels of total ATP5L2.
RRID:
AB_2836164
Cite Format: Affinity Biosciences Cat# DF3807, RRID:AB_2836164.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AT5L2_HUMAN; ATP synthase H+ transporting mitochondrial F0 complex subunit G2 pseudogene; ATP synthase H+ transporting mitochondrial F1F0 subunit g; ATP synthase H+ transporting mitochondrial Fo complex subunit G2; ATP synthase subunit g 2; ATP synthase subunit g 2 mitochondrial; ATP5K2; ATP5L2; ATPase subunit g 2; mitochondrial;

Immunogens

Immunogen:
Uniprot:

Q7Z4Y8(AT5L2_HUMAN) >>Visit HPA database.

Gene(ID):
ATP5L2(267020)
Sequence:
MAPFVRNLVEKTPALVNAAVTYLKPRLAAFWYYTTVELVPPTPAEIPRAIQSLKKIVSSAQTGSFKQLTVKEALLNGLVATEVSTWFYVREITGKRGIIG

PTMs - Q7Z4Y8 As Substrate

Site PTM Type Enzyme
T42 Phosphorylation
K54 Ubiquitination

Research Backgrounds

Function:

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).

Subcellular Location:

Mitochondrion membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L).

Family&Domains:

Belongs to the ATPase g subunit family.

Restrictive clause

 

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