BMP3 Antibody - #DF3848
| Product: | BMP3 Antibody |
| Catalog: | DF3848 |
| Description: | Rabbit polyclonal antibody to BMP3 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine, Sheep |
| Mol.Wt.: | 55 KD; 53kD(Calculated). |
| Uniprot: | P12645 |
| RRID: | AB_2836205 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3848, RRID:AB_2836205.
Fold/Unfold
BMP-3; BMP-3A; bmp3; BMP3_HUMAN; BMP3A; Bone morphogenetic protein 3 (osteogenic); Bone morphogenetic protein 3; Bone morphogenetic protein 3A; Osteogenin;
Immunogens
- P12645 BMP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGASRLLFLWLGCFCVSLAQGERPKPPFPELRKAVPGDRTAGGGPDSELQPQDKVSEHMLRLYDRYSTVQAARTPGSLEGGSQPWRPRLLREGNTVRSFRAAAAETLERKGLYIFNLTSLTKSENILSATLYFCIGELGNISLSCPVSGGCSHHAQRKHIQIDLSAWTLKFSRNQSQLLGHLSVDMAKSHRDIMSWLSKDITQLLRKAKENEEFLIGFNITSKGRQLPKRRLPFPEPYILVYANDAAISEPESVVSSLQGHRNFPTGTVPKWDSHIRAALSIERRKKRSTGVLLPLQNNELPGAEYQYKKDEVWEERKPYKTLQAQAPEKSKNKKKQRKGPHRKSQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12645 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S68 | O-Glycosylation | Uniprot | |
| T69 | O-Glycosylation | Uniprot | |
| T75 | O-Glycosylation | Uniprot | |
| S83 | O-Glycosylation | Uniprot | |
| T107 | Phosphorylation | Uniprot |
Research Backgrounds
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Secreted.
Expressed in adult and fetal cartilage.
Homodimer; disulfide-linked.
Belongs to the TGF-beta family.
Restrictive clause
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