CLIP2 Antibody - #DF3877

(3)  
Product: CLIP2 Antibody
Catalog: DF3877
Description: Rabbit polyclonal antibody to CLIP2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Sheep
Mol.Wt.: 120 KD; 116kD(Calculated).
Uniprot: Q9UDT6
RRID: AB_2836230

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(91%), Sheep(91%)
Clonality:
Polyclonal
Specificity:
CLIP2 Antibody detects endogenous levels of total CLIP2.
RRID:
AB_2836230
Cite Format: Affinity Biosciences Cat# DF3877, RRID:AB_2836230.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CAP GLY domain containing linker protein 2; CAP-Gly domain-containing linker protein 2; CLIP 115; CLIP; CLIP-115; Clip2; CLIP2_HUMAN; cytoplasmic linker 2; Cytoplasmic linker protein 115; Cytoplasmic linker protein 2; KIAA0291; MGC11333; restin; Similar to RESTIN (CYTOPLASMIC LINKER PROTEIN 170 ALPHA 2); WBSCR3; WBSCR4; Williams Beuren syndrome chromosome region 3; Williams Beuren syndrome chromosome region 4; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndrome chromosomal region 4 protein; WSCR3; WSCR4;

Immunogens

Immunogen:
Uniprot:

Q9UDT6(CLIP2_HUMAN) >>Visit HPA database.

Gene(ID):
CLIP2(7461)
Sequence:
MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAASSKEGSPLHKQSSGPSSSPAAAAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDAHSVESLTAQNLSLHSGTATPPLTSRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGEKDLRLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELTLRRGEIEELQQCLLHSGPPPPDHPDAAEILRLRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATSENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVMEGIKMEHQLELGNLQAKHDLETAMHVKEKEALREKLQEAQEELAGLQRHWRAQLEVQASQHRLELQEAQDQRRDAELRVHELEKLDVEYRGQAQAIEFLKEQISLAEKKMLDYERLQRAEAQGKQEVESLREKLLVAENRLQAVEALCSSQHTHMIESNDISEETIRTKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALESKCKSGEKKVDALLKEKRRLEAELETVSRKTHDASGQLVLISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSDQRRYSLIDRSSAPELLRLQHQLMSTEDALRDALDQAQQVEKLMEAMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
91
Sheep
91
Bovine
73
Dog
73
Chicken
73
Horse
70
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UDT6 As Substrate

Site PTM Type Enzyme
S5 Phosphorylation
K8 Acetylation
S18 Phosphorylation
T23 Phosphorylation
S24 Phosphorylation
S27 Phosphorylation
S30 Phosphorylation
S38 Phosphorylation
S42 Phosphorylation
S49 Phosphorylation
S54 Phosphorylation
T150 Phosphorylation
S154 Phosphorylation
S156 Phosphorylation
S160 Phosphorylation
T177 Phosphorylation
S190 Phosphorylation
S194 Phosphorylation
T198 Phosphorylation
S202 Phosphorylation
S204 Phosphorylation
S207 Phosphorylation
S209 Phosphorylation
S211 Phosphorylation
T267 Phosphorylation
S292 Phosphorylation
T293 Phosphorylation
S294 Phosphorylation
S337 Phosphorylation
S352 Phosphorylation
T354 Phosphorylation
T355 Phosphorylation
K364 Ubiquitination
S432 Phosphorylation
S476 Phosphorylation
S627 Phosphorylation
K650 Acetylation
T824 Phosphorylation
S908 Phosphorylation
S923 Phosphorylation
S973 Phosphorylation

Research Backgrounds

Function:

Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity).

Subcellular Location:

Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Localizes preferentially to the ends of tyrosinated microtubules.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with CLASP1 and CLASP2. Binds preferentially to tyrosinated microtubules, and only marginally to detyrosinated microtubules (By similarity).

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