BORG1 Antibody - #DF3908
| Product: | BORG1 Antibody |
| Catalog: | DF3908 |
| Description: | Rabbit polyclonal antibody to BORG1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog |
| Mol.Wt.: | 28 KD; 22kD(Calculated). |
| Uniprot: | O14613 |
| RRID: | AB_2836261 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3908, RRID:AB_2836261.
Fold/Unfold
Binder of Rho GTPases 1; BORG1; BORG1_HUMAN; CDC42 effector protein (Rho GTPase binding) 2; Cdc42 effector protein 2; Cdc42ep2; CEP2; CRIB-containing BOGR1 protein;
Immunogens
- O14613 BORG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSLLSLHVDLGPSILDDVLQIMDQDLDSMQIPT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O14613 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Phosphorylation | Uniprot | ||
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| Y8 | Phosphorylation | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| T88 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| S101 | Phosphorylation | P28482 (MAPK1) | Uniprot |
| S109 | Phosphorylation | Uniprot | |
| T137 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot |
Research Backgrounds
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Endomembrane system>Peripheral membrane protein. Cytoplasm>Cytoskeleton.
Highly expressed in the heart. Weakly expressed in the pancreas and liver.
Interacts with RHOQ and CDC42 in a GTP-dependent manner, and with SEPT7.
The CRIB domain mediates interaction with CDC42.
Belongs to the BORG/CEP family.
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