BORG2 Antibody - #DF3909
| Product: | BORG2 Antibody |
| Catalog: | DF3909 |
| Description: | Rabbit polyclonal antibody to BORG2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 27~45 KD; 28kD(Calculated). |
| Uniprot: | Q9UKI2 |
| RRID: | AB_2836262 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3909, RRID:AB_2836262.
Fold/Unfold
Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CEP3; CRIB containing BORG2 protein; MSE55 related Cdc42 binding protein; MSE55 related protein; UB1;
Immunogens
- Q9UKI2 BORG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQGNYELLPGNQEKAHLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQALMLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSASQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDLGPSLLDEVLNVMDKNK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UKI2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Phosphorylation | Uniprot | ||
| Y8 | Phosphorylation | Uniprot | |
| K10 | Methylation | Uniprot | |
| K15 | Methylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| Y63 | Phosphorylation | Uniprot | |
| S89 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| S93 | Phosphorylation | Uniprot | |
| T98 | Phosphorylation | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| S108 | Phosphorylation | Uniprot | |
| S124 | Phosphorylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| S144 | Phosphorylation | Uniprot | |
| S157 | Phosphorylation | Uniprot | |
| T164 | Phosphorylation | Uniprot | |
| T218 | Phosphorylation | Uniprot | |
| S220 | Phosphorylation | Uniprot |
Research Backgrounds
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Endomembrane system>Peripheral membrane protein. Cytoplasm>Cytoskeleton.
Highly expressed in the heart and weakly in the brain.
Interacts with RHOQ and CDC42, in a GTP-dependent manner, and with SEPT7.
Belongs to the BORG/CEP family.
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