BORG4 Antibody - #DF3910
| Product: | BORG4 Antibody |
| Catalog: | DF3910 |
| Description: | Rabbit polyclonal antibody to BORG4 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Horse |
| Mol.Wt.: | 36 KD; 38kD(Calculated). |
| Uniprot: | Q9H3Q1 |
| RRID: | AB_2836263 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3910, RRID:AB_2836263.
Fold/Unfold
Binder of Rho GTPases 4; BORG4; BORG4_HUMAN; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; CDC42EP4; CEP4;
Immunogens
Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.
- Q9H3Q1 BORG4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H3Q1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K5 | Methylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| K15 | Ubiquitination | Uniprot | |
| S18 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| T23 | Phosphorylation | Uniprot | |
| R42 | Methylation | Uniprot | |
| T50 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| K75 | Ubiquitination | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| S80 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| S89 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| S140 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| Y255 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| S295 | Phosphorylation | Uniprot | |
| S298 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| S344 | Phosphorylation | Uniprot |
Research Backgrounds
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.
Endomembrane system>Peripheral membrane protein. Cytoplasm>Cytoskeleton.
Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.
Interacts with CDC42 and RHOQ, in a GTP-dependent manner.
Belongs to the BORG/CEP family.
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