CEP76 Antibody - #DF3921
| Product: | CEP76 Antibody |
| Catalog: | DF3921 |
| Description: | Rabbit polyclonal antibody to CEP76 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| Mol.Wt.: | 74 KD; 74kD(Calculated). |
| Uniprot: | Q8TAP6 |
| RRID: | AB_2836274 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3921, RRID:AB_2836274.
Fold/Unfold
C18orf9; Centrosomal protein 76kDa; Centrosomal protein of 76 kDa; CEP 76; Cep76; CEP76_HUMAN; Chromosome 18 open reading frame 9; FLJ12542; HsT1705;
Immunogens
- Q8TAP6 CEP76_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLPPEKASELKQLIHQQLSKMDVHGRIREILAETIREELAPDQQHLSTEDLIKALRRRGIIDDVMKELNFVTDSVEQELPSSPKQPICFDRQSTLKKTNIDPTRRYLYLQVLGGKAFLEHLQEPEPLPGQVCSTFTLCLHYRNQRFRSKPVPCACEPDFHDGFLLEVHRESLGDGTRMADSTTMLSISDPIHMVLIKTDIFGETTLVASYFLEWRSVLGSENGVTSLTVELMGVGTESKVSVGILNIKLEMYPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPSHNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQAARFVNVLGYERAPVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVFDLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHRKDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHFVYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRSVL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8TAP6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| K12 | Ubiquitination | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K85 | Ubiquitination | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K279 | Acetylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| Y323 | Phosphorylation | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K489 | Ubiquitination | Uniprot | |
| S537 | Phosphorylation | Uniprot | |
| K594 | Ubiquitination | Uniprot |
Research Backgrounds
Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole.
Note: Does not localize along the ciliary axoneme.
Interacts with CCP110 and CEP97.
Belongs to the CEP76 family.
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