DHPS Antibody - #DF3987
| Product: | DHPS Antibody |
| Catalog: | DF3987 |
| Description: | Rabbit polyclonal antibody to DHPS |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 45 KD; 41kD(Calculated). |
| Uniprot: | P49366 |
| RRID: | AB_2836347 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3987, RRID:AB_2836347.
Fold/Unfold
Deoxyhypusine synthase; Dhps; DHS; DHYS_HUMAN; DS; MIG13; Migration inducing gene 13;
Immunogens
- P49366 DHYS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49366 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| R38 | Methylation | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| T88 | Phosphorylation | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K205 | Ubiquitination | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K329 | Ubiquitination | Uniprot | |
| K338 | Ubiquitination | Uniprot | |
| K366 | Ubiquitination | Uniprot |
Research Backgrounds
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Homotetramer formed by a dimer of dimers.
Belongs to the deoxyhypusine synthase family.
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