MARCH3 Antibody - #DF4019
| Product: | MARCH3 Antibody |
| Catalog: | DF4019 |
| Description: | Rabbit polyclonal antibody to MARCH3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Rabbit, Chicken, Xenopus |
| Mol.Wt.: | 29 KD; 29kD(Calculated). |
| Uniprot: | Q86UD3 |
| RRID: | AB_2836379 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4019, RRID:AB_2836379.
Fold/Unfold
E3 ubiquitin protein ligase MARCH3; E3 ubiquitin-protein ligase MARCH3; FLJ20096; March 3; MARCH III; MARCH-III; March3; MARH3_HUMAN; Membrane associated RING CH protein III; Membrane associated ring finger (C3HC4) 3; Membrane associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase; Membrane associated RING finger protein 3; Membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; MGC48332; RING finger protein 173; RNF173;
Immunogens
- Q86UD3 MARH3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNVPSNQPSLLGLHSVKRNSKETVV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86UD3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y40 | Phosphorylation | Uniprot | |
| S111 | Phosphorylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| T194 | Phosphorylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| Y211 | Phosphorylation | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | Uniprot |
Research Backgrounds
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Cytoplasmic vesicle membrane>Multi-pass membrane protein. Early endosome membrane>Multi-pass membrane protein.
Interacts with MARCHF2 and STX6.
The RING-CH-type zinc finger domain is required for E3 ligase activity.
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