Product: TUBGCP6 Antibody
Catalog: DF4077
Description: Rabbit polyclonal antibody to TUBGCP6
Application: WB IHC IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 200 KD; 200kD(Calculated).
Uniprot: Q96RT7
RRID: AB_2836451

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
TUBGCP6 Antibody detects endogenous levels of total TUBGCP6.
RRID:
AB_2836451
Cite Format: Affinity Biosciences Cat# DF4077, RRID:AB_2836451.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Gamma tubulin complex component 6; GCP 6; MCCRP; MCPHCR; TUBGCP6; tubulin, gamma complex associated protein 6;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQVMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNADLSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERVGCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVLIGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVGAVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGKTINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTHGHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPRLPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDLSPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCVSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSIFSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA

PTMs - Q96RT7 As Substrate

Site PTM Type Enzyme
K137 Ubiquitination
S173 Phosphorylation
T178 Phosphorylation
T188 Phosphorylation
T210 Phosphorylation
S213 Phosphorylation
S242 Phosphorylation
K322 Ubiquitination
S389 Phosphorylation
S392 Phosphorylation O00444 (PLK4)
Y439 Phosphorylation
Y443 Phosphorylation
S629 Phosphorylation
K638 Ubiquitination
S654 Phosphorylation
S657 Phosphorylation
K669 Ubiquitination
S693 Phosphorylation
K710 Ubiquitination
K746 Ubiquitination
K766 Ubiquitination
S831 Phosphorylation
S852 Phosphorylation
T865 Phosphorylation
T963 Phosphorylation
S964 Phosphorylation
Y1039 Phosphorylation
S1041 Phosphorylation O00444 (PLK4)
S1057 Phosphorylation
S1060 Phosphorylation O00444 (PLK4)
S1068 Phosphorylation O00444 (PLK4)
S1087 Phosphorylation O00444 (PLK4)
S1095 Phosphorylation O00444 (PLK4)
S1111 Phosphorylation
S1114 Phosphorylation O00444 (PLK4)
S1122 Phosphorylation O00444 (PLK4)
S1141 Phosphorylation O00444 (PLK4)
S1149 Phosphorylation O00444 (PLK4)
S1168 Phosphorylation O00444 (PLK4)
S1176 Phosphorylation O00444 (PLK4)
S1195 Phosphorylation O00444 (PLK4)
S1203 Phosphorylation O00444 (PLK4)
S1222 Phosphorylation O00444 (PLK4)
S1230 Phosphorylation O00444 (PLK4)
S1237 Phosphorylation
S1249 Phosphorylation O00444 (PLK4)
S1257 Phosphorylation O00444 (PLK4)
S1283 Phosphorylation
S1296 Phosphorylation
S1397 Phosphorylation
S1437 Phosphorylation O00444 (PLK4)
S1465 Phosphorylation O00444 (PLK4)
S1655 Phosphorylation
T1727 Phosphorylation
S1742 Phosphorylation

Research Backgrounds

Function:

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Subcellular Location:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.

Family&Domains:

Belongs to the TUBGCP family.

Restrictive clause

 

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