GJC2 Antibody - #DF4078
| Product: | GJC2 Antibody |
| Catalog: | DF4078 |
| Description: | Rabbit polyclonal antibody to GJC2 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Chicken, Xenopus |
| Mol.Wt.: | 47 KD; 47kD(Calculated). |
| Uniprot: | Q5T442 |
| RRID: | AB_2836452 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4078, RRID:AB_2836452.
Fold/Unfold
B230382L12Rik; Connexin 46.6; Connexin 47; Connexin-46.6; Connexin-47; Connexin46.6; Connexin47; CX 46.6; Cx 47; Cx46.6; Cx47; CXG2_HUMAN; Gap junction alpha 12 protein; Gap junction alpha-12 protein; Gap junction gamma 2 protein; Gap junction gamma-2 protein; Gap junction protein alpha 12 47kDa; Gap junction protein gamma 2 47kDa; GAP JUNCTION PROTEIN, 47-KD; gap junction protein, gamma 12, 47kDa; gap junction protein, gamma 2, 47kDa; GJA 12; GJA12; GJC 2; Gjc2; HLD 2; HLD2; LMPH1C; MGC105119; MGC130506; OTTHUMP00000037763; PMLDAR; SPG44;
Immunogens
Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles.
- Q5T442 CXG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVWI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5T442 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y232 | Phosphorylation | Uniprot | |
| Y235 | Phosphorylation | Uniprot |
Research Backgrounds
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
Cell membrane>Multi-pass membrane protein. Cell junction>Gap junction.
Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles.
A connexon is composed of a hexamer of connexins. Interacts with TJP1 (By similarity).
Belongs to the connexin family. Gamma-type subfamily.
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