GJC3 Antibody - #DF4082
| Product: | GJC3 Antibody |
| Catalog: | DF4082 |
| Description: | Rabbit polyclonal antibody to GJC3 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Rabbit, Dog |
| Mol.Wt.: | 28 KD; 31kD(Calculated). |
| Uniprot: | Q8NFK1 |
| RRID: | AB_2836456 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4082, RRID:AB_2836456.
Fold/Unfold
Connexin 29; Connexin 30.2; Connexin 31.3; Connexin-30.2; Connexin-31.3; CX23; Cx29; Cx30.2; Cx31.3; CXG3_HUMAN; Gap junction epsilon 1 protein; Gap junction epsilon-1 protein; Gap junction gamma 3 protein; Gap junction gamma-3 protein; Gap junction protein epsilon 1 29kDa; Gap junction protein epsilon 1; Gap junction protein gamma 3 30.2kDa; Gap junction protein gamma 3; GJC 3; GJC3; GJE 1;
Immunogens
CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.
- Q8NFK1 CXG3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NFK1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S227 | Phosphorylation | Uniprot | |
| T234 | Phosphorylation | Uniprot |
Research Backgrounds
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cell membrane>Multi-pass membrane protein. Cell junction>Gap junction.
CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.
A connexon is composed of a hexamer of connexins.
Belongs to the connexin family. Gamma-type subfamily.
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