Product: GIMAP2 Antibody
Catalog: DF4100
Description: Rabbit polyclonal antibody to GIMAP2
Application: WB IF/ICC
Reactivity: Human
Prediction: Rabbit
Mol.Wt.: 38 KD; 38kD(Calculated).
Uniprot: Q9UG22
RRID: AB_2836474

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Rabbit(100%)
Clonality:
Polyclonal
Specificity:
GIMAP2 Antibody detects endogenous levels of total GIMAP2.
RRID:
AB_2836474
Cite Format: Affinity Biosciences Cat# DF4100, RRID:AB_2836474.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

GIMA2_HUMAN; GIMAP2; GTPase IMAP family member 2; GTPase, IMAP family member 2; hIMAP2; IMAP2; Immunity associated protein 2; Immunity-associated protein 2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UG22 GIMA2_HUMAN:

Detected in T-cells.

Sequence:
MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCCLLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UG22 As Substrate

Site PTM Type Enzyme
K14 Ubiquitination
K35 Ubiquitination
S36 Phosphorylation
S41 Phosphorylation
S50 Phosphorylation
K51 Ubiquitination
S54 Phosphorylation
K59 Ubiquitination
T60 Phosphorylation
S62 Phosphorylation
K63 Ubiquitination
S64 Phosphorylation
S67 Phosphorylation
T78 Phosphorylation
S83 Phosphorylation
K170 Ubiquitination
K226 Ubiquitination
K237 Ubiquitination
K240 Ubiquitination
Y246 Phosphorylation
T249 Phosphorylation
K263 Ubiquitination

Research Backgrounds

Function:

The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself.

Subcellular Location:

Lipid droplet.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in T-cells.

Subunit Structure:

Monomer in the presence of bound GDP and in the absence of bound nucleotide. Homodimer in the presence of bound GTP. Can form linear oligomers. Heterodimer with GIMAP7.

Family&Domains:

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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