Product: HNRCL Antibody
Catalog: DF4115
Description: Rabbit polyclonal antibody to HNRCL
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 32 KD; 32kD(Calculated).
Uniprot: O60812
RRID: AB_2836480

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
HNRCL Antibody detects endogenous levels of total HNRCL.
RRID:
AB_2836480
Cite Format: Affinity Biosciences Cat# DF4115, RRID:AB_2836480.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Heterogeneous nuclear ribonucleoprotein C-like 1; HNRCL_HUMAN; hnRNP C-like-1; hnRNP core protein C-like 1; HNRNPCL1; HNRPCL1; RP5-845O24.4;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYGFQRDYYDGMYSFPARVPPPPPIALAVVPSKRQRLSGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEQSKQEVEVKNAKSEEEQSSSSMKKDETHVKMESEGGAEDSAEEGDPLDDDVNEDQGDDQLELIKDDEKEAEEGEDDRDSTNGQDDS

PTMs - O60812 As Substrate

Site PTM Type Enzyme
S3 Phosphorylation
K29 Acetylation
K29 Ubiquitination
K30 Acetylation
K30 Ubiquitination
S31 Phosphorylation
S38 Phosphorylation
K39 Acetylation
K39 Methylation
K39 Ubiquitination
K42 Ubiquitination
K89 Ubiquitination
S107 Phosphorylation
S143 Phosphorylation
K144 Acetylation
S149 Phosphorylation
T152 Phosphorylation
K157 Acetylation
K157 Ubiquitination
S158 Phosphorylation
K163 Acetylation
S164 Phosphorylation
K166 Acetylation
K171 Acetylation
K174 Acetylation
K174 Ubiquitination
K176 Methylation
K176 Ubiquitination
K191 Ubiquitination
K193 Ubiquitination
S196 Phosphorylation
K203 Acetylation
K203 Ubiquitination
K216 Acetylation
K219 Acetylation
S226 Phosphorylation
S227 Phosphorylation
S228 Phosphorylation
T234 Phosphorylation
S240 Phosphorylation
K271 Ubiquitination

Research Backgrounds

Function:

May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs.

Subcellular Location:

Nucleus.
Note: Component of ribonucleosomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the RRM HNRPC family. RALY subfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.