Product: PGRMC2 Antibody
Catalog: DF4158
Description: Rabbit polyclonal antibody to PGRMC2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 25 KD; 24kD(Calculated).
Uniprot: O15173
RRID: AB_2836523

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(82%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(91%)
Clonality:
Polyclonal
Specificity:
PGRMC2 Antibody detects endogenous levels of total PGRMC2.
RRID:
AB_2836523
Cite Format: Affinity Biosciences Cat# DF4158, RRID:AB_2836523.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DG6; Membrane associated progesterone receptor component 2; PMBP; Progesterone membrane binding protein; Progesterone receptor membrane component 2; Steroid receptor protein DG6; PGRMC2; PGRC2_HUMAN; Steroid receptor protein DG6; Progesterone membrane-binding protein;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MAAGDGDVKLGTLGSGSESSNDGGSESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAGAGEESPATSLPRMKKRDFSLEQLRQYDGSRNPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASRGLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDEEDTKDHNKQD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Chicken
91
Zebrafish
82
Xenopus
73
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O15173 As Substrate

Site PTM Type Enzyme
S90 Phosphorylation
T93 Phosphorylation
S94 Phosphorylation
K100 Ubiquitination
S104 Phosphorylation
R109 Methylation
K126 Acetylation
K126 Ubiquitination
K132 Ubiquitination
K135 Ubiquitination
Y143 Phosphorylation
R149 Methylation
K162 Acetylation
K162 Ubiquitination
R166 Methylation
Y169 Phosphorylation
S173 Phosphorylation
K191 Ubiquitination
K193 Acetylation
K193 Ubiquitination
Y196 Phosphorylation
K202 Ubiquitination
S208 Phosphorylation
Y210 Phosphorylation
T211 Phosphorylation
T216 Phosphorylation

Research Backgrounds

Function:

Receptor for steroids.

Subcellular Location:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 137 and 161.

Belongs to the cytochrome b5 family. MAPR subfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.