SLC25A11 Antibody - #DF4173
| Product: | SLC25A11 Antibody |
| Catalog: | DF4173 |
| Description: | Rabbit polyclonal antibody to SLC25A11 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 35 KD; 34kD(Calculated). |
| Uniprot: | Q02978 |
| RRID: | AB_2836538 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4173, RRID:AB_2836538.
Fold/Unfold
M2OM_HUMAN; Mitochondrial 2 oxoglutarate/malate carrier protein; Mitochondrial 2-oxoglutarate/malate carrier protein; OGC; OGCP; SLC20A4; SLC25A11; Solute carrier family 20 (oxoglutarate carrier) member 4; Solute carrier family 20 member 4; Solute carrier family 25 (mitochondrial carrier oxoglutarate carrier) member 11; Solute carrier family 25 member 11;
Immunogens
- Q02978 M2OM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02978 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| T4 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| K15 | Ubiquitination | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| T63 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| K73 | Acetylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| R78 | Methylation | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| T103 | Phosphorylation | Uniprot | |
| Y161 | Phosphorylation | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| Y202 | Phosphorylation | Uniprot | |
| S203 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| K256 | Ubiquitination | Uniprot |
Research Backgrounds
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis (By similarity). Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma.
Mitochondrion inner membrane>Multi-pass membrane protein.
Belongs to the mitochondrial carrier (TC 2.A.29) family.
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For Research Use Only.
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