NARFL Antibody - #DF4253
| Product: | NARFL Antibody |
| Catalog: | DF4253 |
| Description: | Rabbit polyclonal antibody to NARFL |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine, Chicken |
| Mol.Wt.: | 50 KD; 53kD(Calculated). |
| Uniprot: | Q9H6Q4 |
| RRID: | AB_2836604 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4253, RRID:AB_2836604.
Fold/Unfold
Cytosolic Fe-S cluster assembly factor NARFL; FLJ21988; HPRN; IOP1; Iron only hydrogenase like protein 1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; Nuclear prelamin A recognition factor like; Nuclear prelamin A recognition factor like protein; nuclear prelamin A recognition factor-like protein; PRN; Protein related to Narf; uclear prelamin A recognition factor-like;
Immunogens
- Q9H6Q4 CIAO3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASPFSGALQLTDLDDFIGPSQECIKPVKVEKRAGSGVAKIRIEDDGSYFQINQDGGTRRLEKAKVSLNDCLACSGCITSAETVLITQQSHEELKKVLDANKMAAPSQQRLVVVSVSPQSRASLAARFQLNPTDTARKLTSFFKKIGVHFVFDTAFSRHFSLLESQREFVRRFRGQADCRQALPLLASACPGWICYAEKTHGSFILPHISTARSPQQVMGSLVKDFFAQQQHLTPDKIYHVTVMPCYDKKLEASRPDFFNQEHQTRDVDCVLTTGEVFRLLEEEGVSLPDLEPAPLDSLCSGASAEEPTSHRGGGSGGYLEHVFRHAARELFGIHVAEVTYKPLRNKDFQEVTLEKEGQVLLHFAMAYGFRNIQNLVQRLKRGRCPYHYVEVMACPSGCLNGGGQLQAPDRPSRELLQHVERLYGMVRAEAPEDAPGVQELYTHWLQGTDSECAGRLLHTQYHAVEKASTGLGIRW
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H6Q4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| S48 | Phosphorylation | Uniprot | |
| Y49 | Phosphorylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| Y239 | Phosphorylation | Uniprot | |
| T242 | Phosphorylation | Uniprot | |
| Y247 | Phosphorylation | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K250 | Ubiquitination | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| Y462 | Phosphorylation | Uniprot | |
| K467 | Ubiquitination | Uniprot |
Research Backgrounds
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Widely expressed.
External component of the CIA complex. In the CIA complex, interacts directly with CIAO1 and MMS19.
Belongs to the NARF family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.