NCOA7 Antibody - #DF4256

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Product: NCOA7 Antibody
Catalog: DF4256
Description: Rabbit polyclonal antibody to NCOA7
Application: WB IF/ICC
Reactivity: Human
Prediction: Rabbit
Mol.Wt.: 106 KD; 106kD(Calculated).
Uniprot: Q8NI08
RRID: AB_2836607

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Rabbit(100%)
Clonality:
Polyclonal
Specificity:
NCOA7 Antibody detects endogenous levels of total NCOA7.
RRID:
AB_2836607
Cite Format: Affinity Biosciences Cat# DF4256, RRID:AB_2836607.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

140 kDa estrogen receptor associated protein; 9030406N13Rik; dJ187J11.3; ERAP140; ESNA1; Estrogen nuclear receptor coactivator 1; FLJ45605; MGC88425; Nbla00052; Nbla10993; Nuclear receptor coactivator 7; RGD1566426;

Immunogens

Immunogen:
Uniprot:

Q8NI08(NCOA7_HUMAN) >>Visit HPA database.

Gene(ID):
NCOA7(135112)
Expression:
Q8NI08 NCOA7_HUMAN:

Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.

Sequence:
MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Sheep
64
Dog
64
Pig
0
Horse
0
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NI08 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S13 Phosphorylation
T38 Phosphorylation
T40 Phosphorylation
Y87 Phosphorylation
Y88 Phosphorylation
S89 Phosphorylation
K109 Ubiquitination
T134 Phosphorylation
S162 Phosphorylation
T166 Phosphorylation
S170 Phosphorylation
S171 Phosphorylation
S173 Phosphorylation
T177 Phosphorylation
S179 Phosphorylation
S181 Phosphorylation
S182 Phosphorylation
S183 Phosphorylation
Y187 Phosphorylation
S208 Phosphorylation
S209 Phosphorylation
T210 Phosphorylation
S211 Phosphorylation
K220 Ubiquitination
K290 Ubiquitination
K317 Ubiquitination
T355 Phosphorylation
T358 Phosphorylation
S363 Phosphorylation
S365 Phosphorylation
S376 Phosphorylation
T380 Phosphorylation
S384 Phosphorylation
S391 Phosphorylation
S395 Phosphorylation
T435 Phosphorylation
S441 Phosphorylation
S500 Phosphorylation
S502 Phosphorylation
K519 Acetylation
K519 Ubiquitination
Y525 Phosphorylation
Y526 Phosphorylation
K531 Ubiquitination
K542 Ubiquitination
S565 Phosphorylation
S596 Phosphorylation
S609 Phosphorylation
S670 Phosphorylation
Y691 Phosphorylation
K756 Ubiquitination
S760 Phosphorylation
T761 Phosphorylation
S763 Phosphorylation
Y765 Phosphorylation
K818 Ubiquitination
K823 Ubiquitination
S918 Phosphorylation
T919 Phosphorylation
S926 Phosphorylation
K927 Ubiquitination

Research Backgrounds

Function:

Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.

Subunit Structure:

Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.

Family&Domains:

Belongs to the OXR1 family.

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