OGFR Antibody - #DF4267

(2)  
Product: OGFR Antibody
Catalog: DF4267
Description: Rabbit polyclonal antibody to OGFR
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 80 KD; 73kD(Calculated).
Uniprot: Q9NZT2
RRID: AB_2836618

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
OGFR Antibody detects endogenous levels of total OGFR.
RRID:
AB_2836618
Cite Format: Affinity Biosciences Cat# DF4267, RRID:AB_2836618.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

7 60 protein; HGNC:15768; Met enkephalin receptor; OGFr; OGFR_HUMAN; Opioid growth factor receptor; Protein 7-60; Zeta type opioid receptor; Zeta-type opioid receptor;

Immunogens

Immunogen:
Uniprot:

Q9NZT2(OGFR_HUMAN) >>Visit HPA database.

Gene(ID):
OGFR(11054)
Expression:
Q9NZT2 OGFR_HUMAN:

Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

Sequence:
MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP

PTMs - Q9NZT2 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S45 Phosphorylation
S55 Phosphorylation
K158 Ubiquitination
Y171 Phosphorylation
Y178 Phosphorylation
T187 Phosphorylation
T189 Phosphorylation
Y196 Phosphorylation
K198 Ubiquitination
K218 Ubiquitination
K283 Ubiquitination
K291 Ubiquitination
K296 Ubiquitination
S299 Phosphorylation
K309 Sumoylation
S315 Phosphorylation
S324 Phosphorylation
T325 Phosphorylation
T329 Phosphorylation
S349 Phosphorylation
S361 Phosphorylation
S378 Phosphorylation P06493 (CDK1)
S382 Phosphorylation
S390 Phosphorylation
S403 Phosphorylation
S420 Phosphorylation
S423 Phosphorylation
T426 Phosphorylation
T428 Phosphorylation
K454 Acetylation
T478 Phosphorylation
S484 Phosphorylation
S488 Phosphorylation
S496 Phosphorylation
S517 Phosphorylation
S525 Phosphorylation
S537 Phosphorylation
S557 Phosphorylation
S577 Phosphorylation
T581 Phosphorylation
S585 Phosphorylation
S597 Phosphorylation
S617 Phosphorylation
S637 Phosphorylation
T641 Phosphorylation
S645 Phosphorylation
T650 Phosphorylation

Research Backgrounds

Function:

Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.

Subcellular Location:

Cytoplasm. Nucleus.
Note: The OGF/OGFR complex is probably translocated to the nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

Family&Domains:

Belongs to the opioid growth factor receptor family.

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