SLC6A15 Antibody - #DF4272
| Product: | SLC6A15 Antibody |
| Catalog: | DF4272 |
| Description: | Rabbit polyclonal antibody to SLC6A15 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Horse, Sheep, Rabbit, Chicken |
| Mol.Wt.: | 85 KD; 82kD(Calculated). |
| Uniprot: | Q9H2J7 |
| RRID: | AB_2836623 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4272, RRID:AB_2836623.
Fold/Unfold
hv7 3; MGC87066; NTT73; Orphan sodium and chloride dependent neurotransmitter transporter NTT73; Orphan transporter v7 3; S6A15_HUMAN; SBAT1; SLC6A15; sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Sodium-dependent neutral amino acid transporter B(0)AT2; Solute carrier family 6 (neutral amino acid transporter) member 15; Solute carrier family 6 member 15; Transporter v7-3; V7 3;
Immunogens
- Q9H2J7 S6A15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPALHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVRRFNLIDDSSGNLASVTYKRGRVLKEPVNLEGDDTSLIHGKIPSEMPSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADIMPDMPESDL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H2J7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S19 | Phosphorylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S55 | Phosphorylation | Uniprot | |
| K658 | Ubiquitination | Uniprot | |
| K664 | Ubiquitination | Uniprot | |
| T674 | Phosphorylation | Uniprot | |
| S675 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| S687 | Phosphorylation | Uniprot | |
| K692 | Ubiquitination | Uniprot | |
| K697 | Ubiquitination | Uniprot | |
| S699 | Phosphorylation | Uniprot | |
| S701 | Phosphorylation | Uniprot |
Research Backgrounds
Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Membrane>Multi-pass membrane protein.
Almost exclusively expressed in the brain.
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
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