PABPC5 Antibody - #DF4303
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4303, RRID:AB_2836654.
Fold/Unfold
PABP5; Poly(A) binding protein 5; Poly(A) binding protein cytoplasmic 5; Polyadenylate binding protein 5;
Immunogens
- Q96DU9 PABP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96DU9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y15 | Phosphorylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| K111 | Acetylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| Y149 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| T199 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| Y270 | Phosphorylation | Uniprot |
Research Backgrounds
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
Cytoplasm.
Mitochondrion matrix.
Note: Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.
Expressed in fetal brain and in a range of adult tissues.
Research Fields
· Genetic Information Processing > Translation > RNA transport.
· Genetic Information Processing > Translation > mRNA surveillance pathway.
· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.
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