Product: RABL2A Antibody
Catalog: DF4374
Description: Rabbit polyclonal antibody to RABL2A
Application: WB IHC IF/ICC
Reactivity: Human
Mol.Wt.: 30-34 KD; 26kD(Calculated).
Uniprot: Q9UBK7
RRID: AB_2836662

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
RABL2A Antibody detects endogenous levels of total RABL2A.
RRID:
AB_2836662
Cite Format: Affinity Biosciences Cat# DF4374, RRID:AB_2836662.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ78724; MGC117180; OTTHUMP00000045491; OTTHUMP00000045492; OTTHUMP00000045493; OTTHUMP00000203788; OTTHUMP00000203792; Rab-like protein 2A; RABL2A; RBL2A_HUMAN; RP11-395L14.2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UBK7 RBL2A_HUMAN:

Expressed in the testis.

Sequence:
MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNLSTWYTELREFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSYKQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEVASPHS

PTMs - Q9UBK7 As Substrate

Site PTM Type Enzyme
K23 Acetylation
K23 Ubiquitination
C26 S-Nitrosylation
K34 Acetylation
K34 Ubiquitination
S35 Acetylation
S52 Phosphorylation
T57 Phosphorylation
Y59 Phosphorylation
T141 Phosphorylation
K143 Ubiquitination
K149 Ubiquitination
K150 Ubiquitination

Research Backgrounds

Function:

Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail.

Tissue Specificity:

Expressed in the testis.

Subunit Structure:

Interacts with IFT27, IFT81, IFT172, ATP6V1E1, HK1, LDHC, MAPRE1 and HSPA2.

Family&Domains:

Belongs to the small GTPase superfamily. Rab family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.