KCNV2 Antibody | Affinity Biosciences

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KCNV2 Antibody - Western blot analysis of extracts from HepG2 cells(heat-shock treatment), using KCNV2 Antibody.

Product:	KCNV2 Antibody
Catalog:	DF4324
Description:	Rabbit polyclonal antibody to KCNV2
Application:	WB IF/ICC
Reactivity:	Human, Mouse
Mol.Wt.:	62 KD; 62kD(Calculated).
Uniprot:	Q8TDN2
RRID:	AB_2836692

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Clonality:

Polyclonal

Specificity:

KCNV2 Antibody detects endogenous levels of total KCNV2.

RRID:

AB_2836692
Cite Format: Affinity Biosciences Cat# DF4324, RRID:AB_2836692.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

KCNV2; KCNV2_HUMAN; KV11.1; Kv8.2; MGC120515; Potassium channel subfamily V member 2; Potassium voltage-gated channel subfamily V member 2; RCD3B; Voltage-gated potassium channel Kv8.2; Voltage-gated potassium channel subunit Kv8.2;

Immunogens

Immunogen:

Uniprot:

Q8TDN2(KCNV2_HUMAN) >>Visit HPA database.

Gene(ID):

KCNV2(169522)

Expression:

Q8TDN2 KCNV2_HUMAN:

Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.

Sequence:

Q8TDN2 KCNV2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MLKQSERRRSWSYRPWNTTENEGSQHRRSICSLGARSGSQASIHGWTEGNYNYYIEEDEDGEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLTPRQEN

PTMs - Q8TDN2 As Substrate

Q8TDN2

Site	PTM Type	Source
Y194	Phosphorylation	Uniprot
T195	Phosphorylation	Uniprot
S323	Phosphorylation	Uniprot
T324	Phosphorylation	Uniprot

Research Backgrounds

Q8TDN2_KCNV2_HUMAN

Function:

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.
Note: Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.

Tissue Specificity:

Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.

Subunit Structure:

Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers.

Family&Domains:

The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.2/KCNV2 sub-subfamily.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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KCNV2 Antibody - #DF4324