ZDHHC20 Antibody - #DF4335
| Product: | ZDHHC20 Antibody |
| Catalog: | DF4335 |
| Description: | Rabbit polyclonal antibody to ZDHHC20 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 37 KD; 42kD(Calculated). |
| Uniprot: | Q5W0Z9 |
| RRID: | AB_2836703 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4335, RRID:AB_2836703.
Fold/Unfold
4933421L13Rik; DHHC-20; Probable palmitoyltransferase ZDHHC20; ZDH20_HUMAN; ZDHHC20; Zinc finger DHHC domain-containing protein 20; Zinc finger DHHC type containing 20;
Immunogens
- Q5W0Z9 ZDH20_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPWTLWRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRLVGMDPEQASVTNQNEYARSSGSNQPFPIKPLSESKNRLLDSESQWLENGAEEGIVKSGTNNHVTVAIEN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5W0Z9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K91 | Ubiquitination | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| T124 | Phosphorylation | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| T307 | Phosphorylation | Uniprot | |
| Y312 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| S328 | Phosphorylation | Uniprot | |
| S330 | Phosphorylation | Uniprot | |
| K331 | Ubiquitination | Uniprot | |
| S339 | Phosphorylation | Uniprot |
Research Backgrounds
Catalyzes palmitoylation of Cys residues on target proteins. Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains.
Autopalmitoylated (in vitro).
Golgi apparatus membrane>Multi-pass membrane protein. Cell membrane>Multi-pass membrane protein. Cytoplasm>Perinuclear region.
The DHHC domain is required for palmitoyltransferase activity.
Belongs to the DHHC palmitoyltransferase family.
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For Research Use Only.
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