RAB26 Antibody - #DF4398
| Product: | RAB26 Antibody |
| Catalog: | DF4398 |
| Description: | Rabbit polyclonal antibody to RAB26 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 28 KD; 28kD(Calculated). |
| Uniprot: | Q9ULW5 |
| RRID: | AB_2836753 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4398, RRID:AB_2836753.
Fold/Unfold
CATX-8; RAB11c; Rab26; RAB26 member RAS oncogene family; RAB26_HUMAN; Ras related oncogene protein; Ras related protein Rab 26; Ras-associated protein Rab26; Ras-related protein Rab-26; V46133;
Immunogens
- Q9ULW5 RAB26_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRKKTPKSKGASTPAASTLPTANGARPARSGTALSGPDAPPNGPLQPGRPSLGGGVDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQRSMKAPSEPRFRLHDYVKREGRGASCCRP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9ULW5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S52 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot |
Research Backgrounds
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.
Golgi apparatus membrane>Lipid-anchor>Cytoplasmic side. Cytoplasmic vesicle>Secretory vesicle membrane>Lipid-anchor>Cytoplasmic side.
Note: Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location.
Predominantly expressed in brain.
Interacts with RIMS1 (By similarity). Interacts with ADRA2B.
Belongs to the small GTPase superfamily. Rab family.
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