RAB40B Antibody - #DF4405

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Product: RAB40B Antibody
Catalog: DF4405
Description: Rabbit polyclonal antibody to RAB40B
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 34 KD; 31kD(Calculated).
Uniprot: Q12829
RRID: AB_2836760

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RAB40B Antibody detects endogenous levels of total RAB40B.
RRID:
AB_2836760
Cite Format: Affinity Biosciences Cat# DF4405, RRID:AB_2836760.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ42385; GTP binding protein homologous to Saccharomyces cerevisiae SEC4; RAB40B member RAS oncogene family; RAR; Rar protein; Ras related protein Rab 40B; RP23 293H17.2; SEC4L; SOCS box containing protein RAR;

Immunogens

Immunogen:
Uniprot:

Q12829(RB40B_HUMAN) >>Visit HPA database.

Gene(ID):
RAB40B(10966)
Sequence:
MSALGSPVRAYDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHAPGVPKILVGNRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFTELARIVLLRHGMDRLWRPSKVLSLQDLCCRAVVSCTPVHLVDKLPLPIALRSHLKSFSMANGLNARMMHGGSYSLTTSSTHKRSSLRKVKLVRPPQSPPKNCTRNSCKIS

PTMs - Q12829 As Substrate

Site PTM Type Enzyme
S2 Phosphorylation
K133 Ubiquitination
S224 Phosphorylation
S226 Phosphorylation
S247 Phosphorylation

Research Backgrounds

Function:

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subcellular Location:

Cell membrane>Lipid-anchor>Cytoplasmic side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.

Belongs to the small GTPase superfamily. Rab family.

Restrictive clause

 

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