RPTN Antibody - #DF4420
| Product: | RPTN Antibody |
| Catalog: | DF4420 |
| Description: | Rabbit polyclonal antibody to RPTN |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine |
| Mol.Wt.: | 91 KD; 91kD(Calculated). |
| Uniprot: | Q6XPR3 |
| RRID: | AB_2836775 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4420, RRID:AB_2836775.
Fold/Unfold
FLJ39117; Intermediate filament associated protein; RPTN;
Immunogens
Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheath and in the filiform papilli of the tongue.
- Q6XPR3 RPTN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNLLDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6XPR3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T53 | Phosphorylation | Uniprot | |
| T56 | Phosphorylation | Uniprot | |
| R175 | Methylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| K233 | Methylation | Uniprot | |
| T247 | Phosphorylation | Uniprot | |
| T252 | Phosphorylation | Uniprot | |
| T262 | Phosphorylation | Uniprot | |
| S412 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| Y415 | Phosphorylation | Uniprot | |
| S613 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.
Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase.
Secreted>Extracellular space>Extracellular matrix.
Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheath and in the filiform papilli of the tongue.
Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats.
Belongs to the S100-fused protein family.
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