ARHGEF3 Antibody - #DF4434
| Product: | ARHGEF3 Antibody |
| Catalog: | DF4434 |
| Description: | Rabbit polyclonal antibody to ARHGEF3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 55 KD; 60kD(Calculated). |
| Uniprot: | Q9NR81 |
| RRID: | AB_2836789 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4434, RRID:AB_2836789.
Fold/Unfold
1200004I24Rik; 59.8 kDA protein; 9830169H03Rik; ARHGEF 3; C76747; DKFZP434F2429; Exchange factor found in platelets and leukemic and neuronal tissues; Exchange factor found in platelets and leukemic and neuronal tissues XPLN; FLJ98126; GEF 3; GEF3; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; Rho guanine nucleotide exchange factor 3; RhoGEF protein; STA 3; STA3; XPLN;
Immunogens
Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
- Q9NR81 ARHG3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NR81 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S43 | Phosphorylation | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| S399 | Phosphorylation | Uniprot | |
| K411 | Ubiquitination | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| K437 | Ubiquitination | Uniprot | |
| S466 | Phosphorylation | Uniprot | |
| S524 | Phosphorylation | Uniprot |
Research Backgrounds
Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
Cytoplasm.
Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
Interacts with RHOA and RHOB.
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