SERGEF Antibody - #DF4452
| Product: | SERGEF Antibody |
| Catalog: | DF4452 |
| Description: | Rabbit polyclonal antibody to SERGEF |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Horse, Rabbit |
| Mol.Wt.: | 50 KD; 49kD(Calculated). |
| Uniprot: | Q9UGK8 |
| RRID: | AB_2836807 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4452, RRID:AB_2836807.
Fold/Unfold
Deafness locus associated putative guanine nucleotide exchange factor; DELGEF; Gef; Gnef; GNEFR; Guanine nucleotide exchange factor related protein; MGC128942; MGC141208; MGC141209; Secretion regulating guanine nucleotide exchange factor; TPH1;
Immunogens
- Q9UGK8 SRGEF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEREPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQLPAHPALVQDPKVTYLSPDAIEDTESQKAMDKERNWKERQSETSTQSQSDWSRNGGL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UGK8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K47 | Ubiquitination | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K256 | Ubiquitination | Uniprot | |
| Y304 | Phosphorylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| Y416 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot |
Research Backgrounds
Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
Cytoplasm. Nucleus.
Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.
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