SEPT14 Antibody - #DF4457
| Product: | SEPT14 Antibody |
| Catalog: | DF4457 |
| Description: | Rabbit polyclonal antibody to SEPT14 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Horse |
| Mol.Wt.: | 50 KD; 50kD(Calculated). |
| Uniprot: | Q6ZU15 |
| RRID: | AB_2836812 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4457, RRID:AB_2836812.
Fold/Unfold
FLJ44060; SEP14_HUMAN; SEPT 14; Sept14; Septin 14; Septin-14; Septin14;
Immunogens
- Q6ZU15 SEP14_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAERTMAMPTQIPADGDTQKENNIRCLTTIGHFGFECLPNQLVSRSIRQGFTFNILCVGETGIGKSTLIDTLFNTNLKDNKSSHFYSNVGLQIQTYELQESNVQLKLTVVETVGYGDQIDKEASYQPIVDYIDAQFEAYLQEELKIKRSLFEYHDSRVHVCLYFISPTGHSLKSLDLLTMKNLDSKVNIIPLIAKADTISKNDLQTFKNKIMSELISNGIQIYQLPTDEETAAQANSSVSGLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHRKK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6ZU15 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S46 | Phosphorylation | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| T366 | Phosphorylation | Uniprot | |
| K391 | Ubiquitination | Uniprot |
Research Backgrounds
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Colocalizes with actin stress fibers.
Testis-specific.
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with SEPTIN9.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
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