SLC6A8 Antibody - #DF4509
| Product: | SLC6A8 Antibody |
| Catalog: | DF4509 |
| Description: | Rabbit polyclonal antibody to SLC6A8 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Rabbit |
| Mol.Wt.: | 71 KD; 71kD(Calculated). |
| Uniprot: | P48029 |
| RRID: | AB_2836860 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4509, RRID:AB_2836860.
Fold/Unfold
SLC6A 8; SLC6A8; Creatine transporter 1; Creatine transporter SLC6A8; CRT; CRTR; CT 1; CT1; MGC87396; SC6A8_HUMAN; Slc6a8; Sodium and chloride-dependent creatine transporter 1; Sodium- and chloride-dependent creatine transporter 1; Solute carrier family 6 (neurotransmitter transporter, creatine), member 8.; Solute carrier family 6 member 8;
Immunogens
Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
- P48029 SC6A8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKKSAENGIYSVSGDEKKGPLIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P48029 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K4 | Ubiquitination | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| Y11 | Phosphorylation | Uniprot | |
| K18 | Acetylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| K19 | Acetylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| T42 | Phosphorylation | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| R614 | Methylation | Uniprot | |
| T617 | Phosphorylation | Uniprot | |
| T618 | Phosphorylation | Uniprot | |
| T620 | Phosphorylation | Uniprot | |
| S623 | Phosphorylation | Uniprot | |
| S625 | Phosphorylation | Uniprot | |
| S626 | Phosphorylation | Uniprot | |
| K627 | Ubiquitination | Uniprot |
Research Backgrounds
Required for the uptake of creatine in muscles and brain.
Membrane>Multi-pass membrane protein.
Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
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