SLC10A7 Antibody - #DF4515
| Product: | SLC10A7 Antibody |
| Catalog: | DF4515 |
| Description: | Rabbit polyclonal antibody to SLC10A7 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 39 KD; 37kD(Calculated). |
| Uniprot: | Q0GE19 |
| RRID: | AB_2836866 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4515, RRID:AB_2836866.
Fold/Unfold
2410193C02Rik; C4orf13; DKFZp313H0531; DKFZp566M114; DKFZp779O2438; MGC25043; Na(+)/bile acid cotransporter 7; NTCP7_HUMAN; P7; PSEC0051; SBF domain containing protein; Slc10a7; Sodium/bile acid cotransporter 7; Solute carrier family 10 (sodium/bile acid cotransporter family), member 7; Solute carrier family 10 member 7;
Immunogens
Widely expressed (PubMed:15932064, PubMed:17628207). Expressed at high levels in liver and at lower levels in prostate, placenta, kidney, heart, lung, thymus and spleen (PubMed:15932064, PubMed:17628207). Strongly expressed in testis and also detected in brain, ovary, colon and small intestine (PubMed:17628207). Weakly expressed in testis and not detected in brain, ovary, colon or small intestine (PubMed:15932064). Isoform 1: Expressed in liver, testis and placenta (PubMed:17628207). Isoform 4: Expressed in liver, testis and placenta (PubMed:17628207).
- Q0GE19 NTCP7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRLLERMRKDWFMVGIVLAIAGAKLEPSIGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSSVLLMIIYTTFCDTFSNPNIDLDKFSLVLILFIIFSIQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q0GE19 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|
Research Backgrounds
Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate).
Cell membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane>Multi-pass membrane protein. Golgi apparatus membrane.
Widely expressed. Expressed at high levels in liver and at lower levels in prostate, placenta, kidney, heart, lung, thymus and spleen. Strongly expressed in testis and also detected in brain, ovary, colon and small intestine. Weakly expressed in testis and not detected in brain, ovary, colon or small intestine. Isoform 1: Expressed in liver, testis and placenta. Isoform 4: Expressed in liver, testis and placenta.
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
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