SFRS8 Antibody - #DF4545

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Product: SFRS8 Antibody
Catalog: DF4545
Description: Rabbit polyclonal antibody to SFRS8
Application: WB IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 105 KD; 105kD(Calculated).
Uniprot: Q12872
RRID: AB_2836896

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(88%)
Clonality:
Polyclonal
Specificity:
SFRS8 Antibody detects endogenous levels of total SFRS8.
RRID:
AB_2836896
Cite Format: Affinity Biosciences Cat# DF4545, RRID:AB_2836896.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1190005N23Rik; 6330437E22Rik; AI197402; AW212079; MGC167082; SFRS 8; Sfrs8 protein; Splicing factor arginine/serine rich 8 (suppressor of white apricot Drosophila homolog); Splicing factor arginine/serine rich 8 (suppressor of white apricot homolog Drosophila); Splicing factor arginine/serine rich 8; Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog; SWAP;

Immunogens

Immunogen:
Uniprot:

Q12872(SFSWA_HUMAN) >>Visit HPA database.

Gene(ID):
SFSWAP(6433)
Sequence:
MYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
88
Zebrafish
75
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q12872 As Substrate

Site PTM Type Enzyme
S15 Phosphorylation
Y90 Phosphorylation
S100 Phosphorylation
Y133 Phosphorylation
Y157 Phosphorylation
S217 Phosphorylation
Y248 Phosphorylation
Y252 Phosphorylation
Y253 Phosphorylation
S273 Phosphorylation
S279 Phosphorylation
S282 Phosphorylation
S283 Phosphorylation
Y296 Phosphorylation
K315 Acetylation
K318 Ubiquitination
K473 Ubiquitination
S561 Phosphorylation
S562 Phosphorylation
S563 Phosphorylation
S604 Phosphorylation
S610 Phosphorylation
T623 Phosphorylation
T642 Phosphorylation
K649 Acetylation
T693 Phosphorylation
S709 Phosphorylation
S743 Phosphorylation
Y774 Phosphorylation
S786 Phosphorylation
S794 Phosphorylation
Y796 Phosphorylation
S802 Phosphorylation
S806 Phosphorylation
S815 Phosphorylation
S824 Phosphorylation
Y829 Phosphorylation
S832 Phosphorylation
S834 Phosphorylation
S838 Phosphorylation
S862 Phosphorylation
S866 Phosphorylation
S868 Phosphorylation
S870 Phosphorylation
S889 Phosphorylation
S891 Phosphorylation
S893 Phosphorylation
S897 Phosphorylation
S900 Phosphorylation
S901 Phosphorylation
S905 Phosphorylation
S909 Phosphorylation
S917 Phosphorylation
K927 Ubiquitination
K935 Acetylation
K935 Ubiquitination
K944 Ubiquitination

Research Backgrounds

Function:

Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

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