STMN3 Antibody - #DF4546
| Product: | STMN3 Antibody |
| Catalog: | DF4546 |
| Description: | Rabbit polyclonal antibody to STMN3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
| Mol.Wt.: | 21 KD; 21kD(Calculated). |
| Uniprot: | Q9NZ72 |
| RRID: | AB_2836897 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4546, RRID:AB_2836897.
Fold/Unfold
AI604839; R75323; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Sclip; Stathmin like 3; Stathmin-3; STMN3; STMN3_HUMAN;
Immunogens
- Q9NZ72 STMN3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NZ72 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| Y8 | Phosphorylation | Uniprot | |
| K9 | Ubiquitination | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| Y37 | Phosphorylation | Uniprot | |
| S50 | Phosphorylation | Uniprot | |
| S53 | Phosphorylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| S60 | Phosphorylation | P49840 (GSK3A) | Uniprot |
| S65 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | P28482 (MAPK1) , Q00535 (CDK5) | Uniprot |
| S72 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Q00535 (CDK5) | Uniprot |
| K78 | Acetylation | Uniprot | |
| T80 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K87 | Acetylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| Y138 | Phosphorylation | Uniprot | |
| S179 | Phosphorylation | Uniprot |
Research Backgrounds
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.
Golgi apparatus. Cell projection>Growth cone. Cell projection>Axon. Cytoplasm>Cytosol.
Neuron specific.
Interacts with STAT3. Interacts with CLU (secreted form); this interaction may act as an important modulator during neuronal differentiation (By similarity).
Belongs to the stathmin family.
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For Research Use Only.
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