Product: USP38 Antibody
Catalog: DF4591
Description: Rabbit polyclonal antibody to USP38
Application: WB IF/ICC
Reactivity: Human, Rat
Prediction: Bovine, Horse, Rabbit, Dog
Mol.Wt.: 117 KD; 117kD(Calculated).
Uniprot: Q8NB14
RRID: AB_2836955

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Prediction:
Bovine(80%), Horse(80%), Rabbit(90%), Dog(80%)
Clonality:
Polyclonal
Specificity:
USP38 Antibody detects endogenous levels of total USP38.
RRID:
AB_2836955
Cite Format: Affinity Biosciences Cat# DF4591, RRID:AB_2836955.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

KIAA1891; Deubiquitinating enzyme 38; HP43.8KD; Ubiquitin carboxyl terminal hydrolase 38; Ubiquitin carboxyl-terminal hydrolase 38; Ubiquitin specific peptidase 38; Ubiquitin specific processing protease 38; Ubiquitin thioesterase 38; Ubiquitin thiolesterase 38; Ubiquitin-specific-processing protease 38; UBP38_HUMAN; USP 38; USP38;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q8NB14 UBP38_HUMAN:

Highly expressed in skeletal muscle. Expressed in adrenal gland.

Sequence:
MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLSLAFCPSSSLENMSVQDPASSPSIQDGGLMQASVPGPSEEPVVYNPTTAAFICDSLVNEKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
90
Horse
80
Bovine
80
Dog
80
Sheep
70
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NB14 As Substrate

Site PTM Type Enzyme
K162 Ubiquitination
Y503 Phosphorylation
S512 Phosphorylation
R535 Methylation
K588 Ubiquitination
S680 Phosphorylation
K773 Ubiquitination
K779 Ubiquitination
S785 Phosphorylation
K795 Ubiquitination
K823 Ubiquitination
K825 Ubiquitination
K907 Ubiquitination
K931 Acetylation
K985 Ubiquitination

Research Backgrounds

Function:

Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked ubiquitin chains.

Tissue Specificity:

Highly expressed in skeletal muscle. Expressed in adrenal gland.

Family&Domains:

Belongs to the peptidase C19 family.

Restrictive clause

 

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For Research Use Only.
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