USP43 Antibody - #DF4593

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Product: USP43 Antibody
Catalog: DF4593
Description: Rabbit polyclonal antibody to USP43
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog
Mol.Wt.: 125 KD; 123kD(Calculated).
Uniprot: Q70EL4
RRID: AB_2836957

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(92%), Bovine(92%), Horse(100%), Sheep(82%), Dog(100%)
Clonality:
Polyclonal
Specificity:
USP43 Antibody detects endogenous levels of total USP43.
RRID:
AB_2836957
Cite Format: Affinity Biosciences Cat# DF4593, RRID:AB_2836957.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Deubiquitinating enzyme 43; Ubiquitin carboxyl-terminal hydrolase 43; ubiquitin specific peptidase 43; Ubiquitin specific protease 43; Ubiquitin thioesterase 43; Ubiquitin thiolesterase 43; Ubiquitin-specific-processing protease 43; UBP43; UBP43_HUMAN; Usp43;

Immunogens

Immunogen:
Uniprot:

Q70EL4(UBP43_HUMAN) >>Visit HPA database.

Gene(ID):
USP43(124739)
Expression:
Q70EL4 UBP43_HUMAN:

Expressed in brain, aorta and lung at low levels.

Sequence:
MDLGPGDAAGGGPLAPRPRRRRSLRRLFSRFLLALGSRSRPGDSPPRPQPGHCDGDGEGGFACAPGPVPAAPGSPGEERPPGPQPQLQLPAGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPADEVILVELYPSGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPSQGTLSAHPLGLSASPRLAAREGQRFSLSLHSESKVLILFCNLVGSGQQASRFGPPFLIREDRAVSWAQLQQSILSKVRHLMKSEAPVQNLGSLFSIRVVGLSVACSYLSPKDSRPLCHWAVDRVLHLRRPGGPPHVKLAVEWDSSVKERLFGSLQEERAQDADSVWQQQQAHQQHSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCNHHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSHAGSTRGSLLSWSSAPCPSLPQVPDSPIFTNSLCNQEKGGLEPRRLVRGVKGRSISMKAPTTSRAKQGPFKTMPLRWSFGSKEKPPGASVELVEYLESRRRPRSTSQSIVSLLTGTAGEDEKSASPRSNVALPANSEDGGRAIERGPAGVPCPSAQPNHCLAPGNSDGPNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTSELDRPLQGTLTLLRSVFRKKENRRNERAEVSPQVPPVSLVSGGLSPAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSSLRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Pig
92
Bovine
92
Sheep
82
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q70EL4 As Substrate

Site PTM Type Enzyme
T283 Phosphorylation
S304 Phosphorylation
T305 Phosphorylation
S391 Phosphorylation
S413 Phosphorylation
S507 Phosphorylation
S508 Phosphorylation
S611 Phosphorylation
S731 Phosphorylation
S766 Phosphorylation
T812 Phosphorylation
S818 Phosphorylation
Y835 Phosphorylation
S844 Phosphorylation
S846 Phosphorylation
S848 Phosphorylation
S876 Phosphorylation
S969 Phosphorylation
T985 Phosphorylation
T997 Phosphorylation
S1041 Phosphorylation
R1053 Methylation
S1065 Phosphorylation
R1071 Methylation
R1081 Methylation
S1088 Phosphorylation
S1098 Phosphorylation
Y1099 Phosphorylation
Y1107 Phosphorylation
T1109 Phosphorylation
S1111 Phosphorylation

Research Backgrounds

Function:

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).

Tissue Specificity:

Expressed in brain, aorta and lung at low levels.

Family&Domains:

Belongs to the peptidase C19 family.

Restrictive clause

 

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