USP45 Antibody - #DF4595
| Product: | USP45 Antibody |
| Catalog: | DF4595 |
| Description: | Rabbit polyclonal antibody to USP45 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit |
| Mol.Wt.: | 90 KD; 92kD(Calculated). |
| Uniprot: | Q70EL2 |
| RRID: | AB_2836959 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4595, RRID:AB_2836959.
Fold/Unfold
Deubiquitinating enzyme 45; Ubiquitin carboxyl-terminal hydrolase 45; Ubiquitin thiolesterase 45; Ubiquitin-specific-processing protease 45; UBP45_HUMAN; Usp45;
Immunogens
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium (PubMed:30573563).
- Q70EL2 UBP45_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAGKLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q70EL2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K156 | Ubiquitination | Uniprot | |
| S271 | Phosphorylation | Uniprot | |
| K391 | Ubiquitination | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| S597 | Phosphorylation | Uniprot | |
| S599 | Phosphorylation | Uniprot | |
| Y666 | Phosphorylation | Uniprot |
Research Backgrounds
May be involved in the maintenance of photoreceptor function.
Photoreceptor inner segment.
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
Belongs to the peptidase C19 family.
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