Product: ZNF420 Antibody
Catalog: DF4627
Description: Rabbit polyclonal antibody to ZNF420
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Bovine, Sheep, Dog
Mol.Wt.: 80 KD; 80kD(Calculated).
Uniprot: Q8TAQ5
RRID: AB_2836991

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(100%), Sheep(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
ZNF420 Antibody detects endogenous levels of total ZNF420.
RRID:
AB_2836991
Cite Format: Affinity Biosciences Cat# DF4627, RRID:AB_2836991.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

APAK; ATM and p53 associated KZNF protein; FLJ32191; Zinc finger protein 420; ZNF 420;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MARKLVMFRDVAIDFSQEEWECLDSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENCDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDFSHGSQVYM

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Dog
100
Xenopus
62
Pig
0
Horse
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8TAQ5 As Substrate

Site PTM Type Enzyme
Y39 Phosphorylation
S40 Phosphorylation
S44 Phosphorylation
S68 Phosphorylation Q13315 (ATM)
T162 Phosphorylation
K170 Sumoylation
T190 Phosphorylation
K198 Ubiquitination
T218 Phosphorylation
K221 Ubiquitination
K224 Sumoylation
K224 Ubiquitination
K230 Ubiquitination
S236 Phosphorylation
T246 Phosphorylation
K249 Ubiquitination
K254 Sumoylation
T274 Phosphorylation
T302 Phosphorylation
K310 Sumoylation
T358 Phosphorylation
K361 Ubiquitination
K364 Sumoylation
K364 Ubiquitination
K370 Ubiquitination
S376 Phosphorylation
K394 Sumoylation
T414 Phosphorylation
K422 Ubiquitination
K426 Acetylation
T442 Phosphorylation
K450 Sumoylation
T470 Phosphorylation
K478 Sumoylation
S488 Phosphorylation
T498 Phosphorylation
T526 Phosphorylation
K529 Sumoylation
T554 Phosphorylation
K562 Ubiquitination
K566 Ubiquitination
S572 Phosphorylation
T582 Phosphorylation
K590 Sumoylation
T610 Phosphorylation
K622 Sumoylation
T638 Phosphorylation
K646 Ubiquitination

Research Backgrounds

Function:

May be involved in transcriptional regulation.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

Restrictive clause

 

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For Research Use Only.
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