Product: ZNF460 Antibody
Catalog: DF4628
Description: Rabbit polyclonal antibody to ZNF460
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 64 KD; 64kD(Calculated).
Uniprot: Q14592
RRID: AB_2836992

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
ZNF460 Antibody detects endogenous levels of total ZNF460.
RRID:
AB_2836992
Cite Format: Affinity Biosciences Cat# DF4628, RRID:AB_2836992.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HZF 8; HZF8; Zinc finger protein 272; Zinc finger protein 460; Zinc finger protein HZF8; ZN460_HUMAN; ZNF 272; ZNF 460; ZNF272; ZNF460;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q14592 ZN460_HUMAN:

Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.

Sequence:
MAAAWMAPAQESVTFEDVAVTFTQEEWGQLDVTQRALYVEVMLETCGLLVALGDSTKPETVEPIPSHLALPEEVSLQEQLAQGVPRYSYLGQAMDQDGPSEMQEYFLRPGTDPQSEKLHGKMSLEHEGLATADGICSMMIQNQVSPEDALYGFDSYGPVTDSLIHEGENSYKFEEMFNENCFLVQHEQILPRVKPYDCPECGKAFGKSKHLLQHHIIHTGEKPYKCLECGKDFNRRSHLTRHQRTHNGDKPFVCSECGRTFNRGSHLTRHQRVHSGEKPFVCNECGKAFTYRSNFVLHNKSHNEKKPFACSECGKGFYESTALIQHFIIHTGERPFKCLECGKAFNCRSHLKQHERIHTGEKPFVCSQCGKAFTHYSTYVLHERAHTGEKPFECKECGKAFSIRKDLIRHFNIHTGEKPYECLQCGKAFTRMSGLTRHQWIHTGEKPYVCIQCGKAFCRTTNLIRHFSIHTGEKPYECVECGKAFNRRSPLTRHQRIHTAEKSHEPIQSGNVSCESTDLIQHSIIHTESSPVSAVNMETPSIAAHSSSLDINGFIVEETLPL

PTMs - Q14592 As Substrate

Site PTM Type Enzyme
K117 Ubiquitination
S170 Phosphorylation
Y171 Phosphorylation
K194 Sumoylation
K194 Ubiquitination
K203 Sumoylation
K203 Ubiquitination
K209 Sumoylation
T219 Phosphorylation
K222 Ubiquitination
K225 Sumoylation
K231 Ubiquitination
K250 Sumoylation
K250 Ubiquitination
S275 Phosphorylation
K278 Sumoylation
K278 Ubiquitination
K287 Ubiquitination
K300 Sumoylation
K300 Ubiquitination
K305 Ubiquitination
K306 Sumoylation
K306 Ubiquitination
T331 Phosphorylation
K337 Sumoylation
K337 Ubiquitination
K343 Ubiquitination
T359 Phosphorylation
K362 Sumoylation
K362 Ubiquitination
S367 Phosphorylation
T387 Phosphorylation
K390 Sumoylation
K390 Ubiquitination
K395 Sumoylation
K395 Ubiquitination
K399 Sumoylation
K399 Ubiquitination
T415 Phosphorylation
K418 Ubiquitination
Y420 Phosphorylation
K427 Sumoylation
K427 Ubiquitination
T443 Phosphorylation
K446 Sumoylation
K446 Ubiquitination
K455 Sumoylation
S468 Phosphorylation
T471 Phosphorylation
K474 Ubiquitination
Y476 Phosphorylation
K483 Sumoylation
K483 Ubiquitination
S489 Phosphorylation

Research Backgrounds

Function:

May be involved in transcriptional regulation.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.

Family&Domains:

Belongs to the krueppel C2H2-type zinc-finger protein family.

Restrictive clause

 

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For Research Use Only.
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