RNF130 Antibody - #DF4654
| Product: | RNF130 Antibody |
| Catalog: | DF4654 |
| Description: | Rabbit polyclonal antibody to RNF130 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 36 KD; 46kD(Calculated). |
| Uniprot: | Q86XS8 |
| RRID: | AB_2837005 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4654, RRID:AB_2837005.
Fold/Unfold
2510042A13Rik; G1 related zinc finger protein; G1rp; G1RZFP; GOLIATH; GP; MGC117241; MGC138647; MGC99542; R goliath; RING finger protein 130;
Immunogens
Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.
- Q86XS8 GOLI_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSCAGRAGPARLAALALLTCSLWPARADNASQEYYTALINVTVQEPGRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLAGDNSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86XS8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N40 | N-Glycosylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| S210 | Phosphorylation | Uniprot | |
| Y216 | Phosphorylation | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| K283 | Ubiquitination | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| T372 | Phosphorylation | Uniprot |
Research Backgrounds
May have a role during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin-protein ligase.
In vivo measurements suggest this protein is glycosylated. In contrast, in vitro experiments failed to detect glycosylation.
Membrane>Single-pass type I membrane protein. Cytoplasm.
Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.
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