Product: LIPB1 Antibody
Catalog: DF4665
Description: Rabbit polyclonal antibody to LIPB1
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 115 KD; 114kD(Calculated).
Uniprot: Q86W92
RRID: AB_2837016

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(90%)
Clonality:
Polyclonal
Specificity:
LIPB1 Antibody detects endogenous levels of total LIPB1.
RRID:
AB_2837016
Cite Format: Affinity Biosciences Cat# DF4665, RRID:AB_2837016.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

PPFIBP 1; hSGT2; hSgt2p; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q86W92 LIPB1_HUMAN:

Widely expressed. Absent in liver.

Sequence:
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Chicken
90
Xenopus
70
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q86W92 As Substrate

Site PTM Type Enzyme
Y28 Phosphorylation
S29 Phosphorylation
S37 Phosphorylation
T39 Phosphorylation
S40 Phosphorylation
S45 Phosphorylation
T64 Phosphorylation
K67 Ubiquitination
T163 Phosphorylation
K169 Ubiquitination
K188 Ubiquitination
Y193 Phosphorylation
K196 Ubiquitination
K213 Acetylation
Y250 Phosphorylation
S268 Phosphorylation
K270 Ubiquitination
K286 Ubiquitination
K310 Ubiquitination
K322 Acetylation
K338 Ubiquitination
T342 Phosphorylation
K349 Ubiquitination
Y353 Phosphorylation
S359 Phosphorylation
S364 Phosphorylation
T428 Phosphorylation
S434 Phosphorylation
S460 Phosphorylation
K463 Ubiquitination
S465 Phosphorylation
S466 Phosphorylation
K471 Ubiquitination
T474 Phosphorylation
S475 Phosphorylation
K479 Acetylation
S523 Phosphorylation
S524 Phosphorylation
R527 Methylation
T538 Phosphorylation
S540 Phosphorylation
T547 Phosphorylation
K549 Ubiquitination
S567 Phosphorylation
S571 Phosphorylation
S579 Phosphorylation
S582 Phosphorylation
S599 Phosphorylation
S601 Phosphorylation
T602 Phosphorylation
T603 Phosphorylation
S610 Phosphorylation
K615 Acetylation
K615 Methylation
K615 Ubiquitination
T622 Phosphorylation
S630 Phosphorylation
S636 Phosphorylation
S638 Phosphorylation
K646 Ubiquitination
S682 Phosphorylation
K693 Ubiquitination
S695 Phosphorylation
K737 Ubiquitination
Y752 Phosphorylation
T754 Phosphorylation
S760 Phosphorylation
S794 Phosphorylation
T798 Phosphorylation
S802 Phosphorylation
T860 Phosphorylation
Y891 Phosphorylation
T895 Phosphorylation
Y924 Phosphorylation
K940 Ubiquitination
K943 Ubiquitination
Y951 Phosphorylation
S965 Phosphorylation
T983 Phosphorylation
K993 Ubiquitination
S999 Phosphorylation
S1001 Phosphorylation
S1003 Phosphorylation
T1005 Phosphorylation
S1009 Phosphorylation

Research Backgrounds

Function:

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.

Tissue Specificity:

Widely expressed. Absent in liver.

Subunit Structure:

Forms homodimers and heterodimers. Interacts with S100A4 in a calcium-dependent mode.

Family&Domains:

The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type beta/beta. The C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha and interaction with S100A4.

Belongs to the liprin family. Liprin-beta subfamily.

Restrictive clause

 

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