LIPB1 Antibody - #DF4665
Product: | LIPB1 Antibody |
Catalog: | DF4665 |
Description: | Rabbit polyclonal antibody to LIPB1 |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
Mol.Wt.: | 115 KD; 114kD(Calculated). |
Uniprot: | Q86W92 |
RRID: | AB_2837016 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4665, RRID:AB_2837016.
Fold/Unfold
PPFIBP 1; hSGT2; hSgt2p; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2;
Immunogens
- Q86W92 LIPB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86W92 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y28 | Phosphorylation | Uniprot | |
S29 | Phosphorylation | Uniprot | |
S37 | Phosphorylation | Uniprot | |
T39 | Phosphorylation | Uniprot | |
S40 | Phosphorylation | Uniprot | |
S45 | Phosphorylation | Uniprot | |
T64 | Phosphorylation | Uniprot | |
K67 | Ubiquitination | Uniprot | |
T163 | Phosphorylation | Uniprot | |
K169 | Ubiquitination | Uniprot | |
K188 | Ubiquitination | Uniprot | |
Y193 | Phosphorylation | Uniprot | |
K196 | Ubiquitination | Uniprot | |
K213 | Acetylation | Uniprot | |
Y250 | Phosphorylation | Uniprot | |
S268 | Phosphorylation | Uniprot | |
K270 | Ubiquitination | Uniprot | |
K286 | Ubiquitination | Uniprot | |
K310 | Ubiquitination | Uniprot | |
K322 | Acetylation | Uniprot | |
K338 | Ubiquitination | Uniprot | |
T342 | Phosphorylation | Uniprot | |
K349 | Ubiquitination | Uniprot | |
Y353 | Phosphorylation | Uniprot | |
S359 | Phosphorylation | Uniprot | |
S364 | Phosphorylation | Uniprot | |
T428 | Phosphorylation | Uniprot | |
S434 | Phosphorylation | Uniprot | |
S460 | Phosphorylation | Uniprot | |
K463 | Ubiquitination | Uniprot | |
S465 | Phosphorylation | Uniprot | |
S466 | Phosphorylation | Uniprot | |
K471 | Ubiquitination | Uniprot | |
T474 | Phosphorylation | Uniprot | |
S475 | Phosphorylation | Uniprot | |
K479 | Acetylation | Uniprot | |
S523 | Phosphorylation | Uniprot | |
S524 | Phosphorylation | Uniprot | |
R527 | Methylation | Uniprot | |
T538 | Phosphorylation | Uniprot | |
S540 | Phosphorylation | Uniprot | |
T547 | Phosphorylation | Uniprot | |
K549 | Ubiquitination | Uniprot | |
S567 | Phosphorylation | Uniprot | |
S571 | Phosphorylation | Uniprot | |
S579 | Phosphorylation | Uniprot | |
S582 | Phosphorylation | Uniprot | |
S599 | Phosphorylation | Uniprot | |
S601 | Phosphorylation | Uniprot | |
T602 | Phosphorylation | Uniprot | |
T603 | Phosphorylation | Uniprot | |
S610 | Phosphorylation | Uniprot | |
K615 | Acetylation | Uniprot | |
K615 | Methylation | Uniprot | |
K615 | Ubiquitination | Uniprot | |
T622 | Phosphorylation | Uniprot | |
S630 | Phosphorylation | Uniprot | |
S636 | Phosphorylation | Uniprot | |
S638 | Phosphorylation | Uniprot | |
K646 | Ubiquitination | Uniprot | |
S682 | Phosphorylation | Uniprot | |
K693 | Ubiquitination | Uniprot | |
S695 | Phosphorylation | Uniprot | |
K737 | Ubiquitination | Uniprot | |
Y752 | Phosphorylation | Uniprot | |
T754 | Phosphorylation | Uniprot | |
S760 | Phosphorylation | Uniprot | |
S794 | Phosphorylation | Uniprot | |
T798 | Phosphorylation | Uniprot | |
S802 | Phosphorylation | Uniprot | |
T860 | Phosphorylation | Uniprot | |
Y891 | Phosphorylation | Uniprot | |
T895 | Phosphorylation | Uniprot | |
Y924 | Phosphorylation | Uniprot | |
K940 | Ubiquitination | Uniprot | |
K943 | Ubiquitination | Uniprot | |
Y951 | Phosphorylation | Uniprot | |
S965 | Phosphorylation | Uniprot | |
T983 | Phosphorylation | Uniprot | |
K993 | Ubiquitination | Uniprot | |
S999 | Phosphorylation | Uniprot | |
S1001 | Phosphorylation | Uniprot | |
S1003 | Phosphorylation | Uniprot | |
T1005 | Phosphorylation | Uniprot | |
S1009 | Phosphorylation | Uniprot |
Research Backgrounds
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Widely expressed. Absent in liver.
Forms homodimers and heterodimers. Interacts with S100A4 in a calcium-dependent mode.
The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type beta/beta. The C-terminal, non-coiled coil regions mediate heterodimerization type beta/alpha and interaction with S100A4.
Belongs to the liprin family. Liprin-beta subfamily.
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