Product: CLPT1 Antibody
Catalog: DF4862
Description: Rabbit polyclonal antibody to CLPT1
Application: WB IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 74 KD; 76kD(Calculated).
Uniprot: O96005
RRID: AB_2837226

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
CLPT1 Antibody detects endogenous levels of total CLPT1.
RRID:
AB_2837226
Cite Format: Affinity Biosciences Cat# DF4862, RRID:AB_2837226.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cleft lip and palate associated transmembrane protein 1; CLPTM 1; CLPTM1 transmembrane protein; HS9; N14;

Immunogens

Immunogen:

A synthesized peptide derived from human CLPT1, corresponding to a region within the internal amino acids.

Uniprot:
Gene(ID):
Expression:
O96005 CLPT1_HUMAN:

Widely expressed.

Sequence:
MAAAQEADGARSAVVAAGGGSSGQVTSNGSIGRDPPAETQPQNPPAQPAPNAWQVIKGVLFRIFIIWAISSWFRRGPAPQDQAGPGGAPRVASRNLFPKDTLMNLHVYISEHEHFTDFNATSALFWEQHDLVYGDWTSGENSDGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQKALYRRLATVHMSRMINKYKRRRFQKTKNLLTGETEADPEMIKRAEDYGPVEVISHWHPNITINIVDDHTPWVKGSVPPPLDQYVKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQLYAAQSTKSPWNFLGDELYEQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKNDIQFWNSRQSLEGLSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRLDREHRVAGIFPRLSFKDKSTYIESSTKVYDDMAFRYLSWILFPLLGCYAVYSLLYLEHKGWYSWVLSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGCLRDDVVFFIYLYQRWIYRVDPTRVNEFGMSGEDPTAAAPVAEVPTAAGALTPTPAPTTTTATREEASTSLPTKPTQGASSASEPQEAPPKPAEDKKKD

PTMs - O96005 As Substrate

Site PTM Type Enzyme
A2 Acetylation
K209 Ubiquitination
T213 Phosphorylation
T216 Phosphorylation
K224 Ubiquitination
K267 Ubiquitination
Y275 Phosphorylation
Y280 Phosphorylation
Y284 Phosphorylation
N295 N-Glycosylation
S306 Phosphorylation
S311 Phosphorylation
K324 Ubiquitination
S338 Phosphorylation
K436 Ubiquitination
K458 Ubiquitination
K460 Ubiquitination
K534 Ubiquitination
S601 Phosphorylation
T616 Phosphorylation
T622 Phosphorylation
T628 Phosphorylation
K644 Ubiquitination

Research Backgrounds

Function:

May play a role in T-cell development.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Family&Domains:

Belongs to the CLPTM1 family.

Restrictive clause

 

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