GPR107 Antibody - #DF4939
| Product: | GPR107 Antibody |
| Catalog: | DF4939 |
| Description: | Rabbit polyclonal antibody to GPR107 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Horse |
| Mol.Wt.: | 67 KD; 67kD(Calculated). |
| Uniprot: | Q5VW38 |
| RRID: | AB_2837292 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4939, RRID:AB_2837292.
Fold/Unfold
bA138E2.2; DKFZp667C222; FLJ16312; FLJ20998; FLJ22591; G protein coupled receptor 107; GCDRP; GPR 107; KIAA1624; Lung seven transmembrane receptor 1; LUSTR1; MGC126118; MGC15440; protein GPR107; RP11 88G17;
Immunogens
- Q5VW38 GP107_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAALAPVGSPASRGPRLAAGLRLLPMLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSLNEPEDKDVTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSVSVTLLILDISRSEVRVKSPPEAGTQLPKIIFSRDEKVLGQSQEPNVNPASAGNQTQKTQDGGKSKRSTVDSKAMGEKSFSVHNNGGAVSFQFFFNISTDDQEGLYSLYFHKCLGKELPSDKFTFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKGDSMGPLQQRANLRAGSRIESHHFAQADLELLASSCPPASVSQRAGITAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEEDLEMESVVTTSGVMESMKKVKKVTNGSVEPQGEWEGAV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5VW38 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T85 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| S157 | O-Glycosylation | Uniprot | |
| S166 | O-Glycosylation | Uniprot | |
| T171 | O-Glycosylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| K584 | Ubiquitination | Uniprot |
Research Backgrounds
Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).
(Microbial infection) Required for intoxication by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT. May contribute to the retrograde transport of bacterial toxins, including cholera toxin, from the trans-Golgi network to the endoplasmic reticulum.
Cleaved by FURIN to yield two fragments of 17 and 35 kDa that remain associated via a disulfide bond.
Cell membrane>Multi-pass membrane protein. Golgi apparatus>trans-Golgi network membrane.
Belongs to the LU7TM family.
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