GPR17 Antibody - #DF4966
| Product: | GPR17 Antibody |
| Catalog: | DF4966 |
| Description: | Rabbit polyclonal antibody to GPR17 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 40 KD; 41kD(Calculated). |
| Uniprot: | Q13304 |
| RRID: | AB_2837319 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4966, RRID:AB_2837319.
Fold/Unfold
DKFZp686M18273; G protein coupled receptor 17; G-protein coupled receptor 17; GPR 17; Gpr17; GPR17_HUMAN; P2Y like receptor; P2Y-like receptor; Probable P2Y purinoceptor GPR 17; Probable P2Y purinoceptor GPR17; R12; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor;
Immunogens
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
- Q13304 GPR17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13304 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S246 | Phosphorylation | Uniprot | |
| Y325 | Phosphorylation | Uniprot |
Research Backgrounds
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Cell membrane>Multi-pass membrane protein.
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
Belongs to the G-protein coupled receptor 1 family.
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