Connexin 26 Antibody - #AF5116

Product: | Connexin 26 Antibody |
Catalog: | AF5116 |
Description: | Rabbit polyclonal antibody to Connexin 26 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
Mol.Wt.: | 26 kDa; 26kD(Calculated). |
Uniprot: | P29033 |
RRID: | AB_2837602 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF5116, RRID:AB_2837602.
Fold/Unfold
connexin 26; Connexin-26; Cx26; CXB2_HUMAN; DFNA3; DFNB1; Gap junction beta-2 protein; GJB2; HID; KID; NSRD1; PPK;
Immunogens
A synthesized peptide derived from human Connexin 26, corresponding to a region within the internal amino acids.
- P29033 CXB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
Cell membrane>Multi-pass membrane protein. Cell junction>Gap junction.
Note: Colocalizes with GJB4 at gap junction plaques in the cochlea.
Belongs to the connexin family. Beta-type (group I) subfamily.
References
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