Trefoil factor 2/TFF2 Antibody - #AF5157

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Product: Trefoil factor 2/TFF2 Antibody
Catalog: AF5157
Description: Rabbit polyclonal antibody to Trefoil factor 2/TFF2
Application: WB IHC
Reactivity: Human
Prediction: Bovine, Sheep, Dog
Mol.Wt.: 14 kDa; 14kD(Calculated).
Uniprot: Q03403
RRID: AB_2837643

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Bovine(82%), Sheep(82%), Dog(91%)
Clonality:
Polyclonal
Specificity:
Trefoil factor 2/TFF2 Antibody detects endogenous levels of total Trefoil factor 2/TFF2.
RRID:
AB_2837643
Cite Format: Affinity Biosciences Cat# AF5157, RRID:AB_2837643.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

SML 1; SML1; SP; Spasmolysin; Spasmolytic polypeptide; spasmolytic protein 1; TFF 2; TFF2; TFF2_HUMAN; trefoil factor 2 (spasmolytic protein 1); Trefoil factor 2; Trefoil factor 2 precursor;

Immunogens

Immunogen:
Uniprot:

Q03403(TFF2_HUMAN) >>Visit HPA database.

Gene(ID):
TFF2(7032)
Expression:
Q03403 TFF2_HUMAN:

Stomach.

Description:
Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains
Sequence:
MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
91
Bovine
82
Sheep
82
Pig
73
Horse
73
Xenopus
50
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q03403 As Substrate

Site PTM Type Enzyme
Y93 Phosphorylation

Research Backgrounds

Function:

Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Stomach.

Restrictive clause

 

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For Research Use Only.
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