DEFB132 Antibody - #DF6219
(1)
Product: | DEFB132 Antibody |
Catalog: | DF6219 |
Description: | Rabbit polyclonal antibody to DEFB132 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Mol.Wt.: | 11kDa; 11kD(Calculated). |
Uniprot: | Q7Z7B7 |
RRID: | AB_2838185 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
DEFB132 Antibody detects endogenous levels of total DEFB132.
RRID:
AB_2838185
Cite Format: Affinity Biosciences Cat# DF6219, RRID:AB_2838185.
Cite Format: Affinity Biosciences Cat# DF6219, RRID:AB_2838185.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
BD-32; beta 132; Beta-defensin 132; Beta-defensin 32; DB132_HUMAN; DEFB-32; DEFB132; Defensin; Defensin HEL-75; UNQ827;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Description:
∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 32, also known as ∫-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.
Sequence:
- Q7Z7B7 DB132_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYSFLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS
Research Backgrounds
Function:
Has antibacterial activity.
Subcellular Location:
Secreted.
Family&Domains:
Belongs to the beta-defensin family.
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