LCN6 Antibody - #DF6336
(2)
| Product: | LCN6 Antibody |
| Catalog: | DF6336 |
| Description: | Rabbit polyclonal antibody to LCN6 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 18kDa; 18kD(Calculated). |
| Uniprot: | P62502 |
| RRID: | AB_2838300 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
LCN6 Antibody detects endogenous levels of total LCN6.
RRID:
AB_2838300
Cite Format: Affinity Biosciences Cat# DF6336, RRID:AB_2838300.
Cite Format: Affinity Biosciences Cat# DF6336, RRID:AB_2838300.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Epididymal specific lipocalin 6; Epididymal specific lipocalin ELP16; Epididymal specific lipocalin LCN6; hLcn5; LCN5; Lipocalin 5; Lipocalin 6; MCG18768; UNQ643;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
Description:
The Lipocalin family is composed of structurally conserved hydrophobic ligand binding proteins and is represented in all major taxonomic groups from prokaryotes to primates. Members of the lipocalin family are characterized by several common molecular-recognition properties: the ability to bind a range of small hydrophobic molecules, binding to specific cell-surface receptors and the formation of complexes with soluble macromolecules. Lipocalin-6, also known as LCN5, hLcn5, UNQ643 or LCN6, is a 163 amino acid protein that is predominantly expressed in epididymis. Lipocalin-6 locatizes to the head and tail of spermatozoa, with the highest concentration on the post-acrosomal region of the head. Belonging to the calycin superfamily, Lipocalin-6 may play a role in sperm maturation. The gene encoding Lipocalin-6 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
Sequence:
- P62502 LCN6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGGLLLAAFLALVSVPRAQAVWLGRLDPEQLLGPWYVLAVASREKGFAMEKDMKNVVGVVVTLTPENNLRTLSSQHGLGGCDQSVMDLIKRNSGWVFENPSIGVLELWVLATNFRDYAIIFTQLEFGDEPFNTVELYSLTETASQEAMGLFTKWSRSLGFLSQ
PTMs - P62502 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S14 | Phosphorylation | Uniprot | |
| K51 | Methylation | Uniprot |
Research Backgrounds
Function:
May play a role in male fertility.
Subcellular Location:
Secreted.
Note: Located on the head and tail of spermatozoa with the highest concentration on the post-acrosomal region of the head, where it appears aggregated into large patches.
Tissue Specificity:
Predominantly expressed in epididymis.
Family&Domains:
Belongs to the calycin superfamily. Lipocalin family.
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For Research Use Only.
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