SCCPDH Antibody - #DF6871
(5)
| Product: | SCCPDH Antibody |
| Catalog: | DF6871 |
| Description: | Rabbit polyclonal antibody to SCCPDH |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 47kDa, 40 kDa; 47kD(Calculated). |
| Uniprot: | Q8NBX0 |
| RRID: | AB_2838830 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(89%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
SCCPDH Antibody detects endogenous levels of total SCCPDH.
RRID:
AB_2838830
Cite Format: Affinity Biosciences Cat# DF6871, RRID:AB_2838830.
Cite Format: Affinity Biosciences Cat# DF6871, RRID:AB_2838830.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
CGI 49; CGI49; FLJ43187; Probable saccharopine dehydrogenase; Saccharopine dehydrogenase; SCCPDH; SCPDH_HUMAN;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Description:
SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Sequence:
- Q8NBX0 SCPDL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATEQRPFHLVVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAALKLGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNKHGIEFSVISSSEV
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Rabbit
100
Chicken
89
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NBX0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K58 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| K359 | Ubiquitination | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| T400 | Phosphorylation | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| S425 | Phosphorylation | Uniprot | |
| S426 | Phosphorylation | Uniprot |
Research Backgrounds
Family&Domains:
Belongs to the saccharopine dehydrogenase family.
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