Parvalbumin Antibody - #DF7083
(1)
| Product: | Parvalbumin Antibody |
| Catalog: | DF7083 |
| Description: | Rabbit polyclonal antibody to Parvalbumin |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Rabbit, Xenopus |
| Mol.Wt.: | 12kDa; 12kD(Calculated). |
| Uniprot: | P20472 |
| RRID: | AB_2839039 |
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(88%), Rabbit(88%), Xenopus(88%)
Clonality:
Polyclonal
Specificity:
Parvalbumin Antibody detects endogenous levels of total Parvalbumin.
RRID:
AB_2839039
Cite Format: Affinity Biosciences Cat# DF7083, RRID:AB_2839039.
Cite Format: Affinity Biosciences Cat# DF7083, RRID:AB_2839039.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
D22S749; MGC116759; Parvalbumin alpha; PRVA_HUMAN; PVALB;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Description:
Parvalbumin is a calcium-binding albumin protein with low molecular weight (typically 9-11 kDa). It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif.
Sequence:
- P20472 PRVA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Bovine
100
Horse
88
Xenopus
88
Rabbit
88
Sheep
0
Dog
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P20472 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| T83 | Phosphorylation | Uniprot | |
| K84 | Acetylation | Uniprot | |
| K97 | Acetylation | Uniprot |
Research Backgrounds
Function:
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Family&Domains:
Belongs to the parvalbumin family.
Restrictive clause
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For Research Use Only.
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